Neural synchrony within the motor system: what have we learned so far?

Synchronization of neural activity is considered essential for information processing in the nervous system. Both local and inter-regional synchronization are omnipresent in different frequency regimes and relate to a variety of behavioral and cognitive functions. Over the years, many studies have sought to elucidate the question how alpha/mu, beta, and gamma synchronization contribute to motor control. Here, we review these studies with the purpose to delineate what they have added to our understanding of the neural control of movement. We highlight important findings regarding oscillations in primary motor cortex, synchronization between cortex and spinal cord, synchronization between cortical regions, as well as abnormal synchronization patterns in a selection of motor dysfunctions. The interpretation of synchronization patterns benefits from combining results of invasive and non-invasive recordings, different data analysis tools, and modeling work. Importantly, although synchronization is deemed to play a vital role, it is not the only mechanism for neural communication. Spike timing and rate coding act together during motor control and should therefore both be accounted for when interpreting movement-related activity

Neural synchronization within and between regions of the motor system

Daffertshofer, A. [Promotor]Beek, P.J. [Promotor

SNAPS : semantic network traffic analysis through projection and selection

Most network traffic analysis applications are designed to discover malicious activity by only relying on high-level flow-based message properties. However, to detect security breaches that are specifically designed to target one network (e.g., Advanced Persistent Threats), deep packet inspection and anomaly detection are indispensible. In this paper, we focus on how we can support experts in discovering whether anomalies at message level imply a security risk at network level. In SNAPS (Semantic Network traffic Analysis through Projection and Selection), we provide a bottom-up pixel-oriented approach for network traffic analysis where the expert starts with low-level anomalies and iteratively gains insight in higher level events through the creation of multiple selections of interest in parallel. The tight integration between visualization and machine learning enables the expert to iteratively refine anomaly scores, making the approach suitable for both post-traffic analysis and online monitoring tasks. To illustrate the effectiveness of this approach, we present example explorations on two real-world data sets for the detection and understanding of potential Advanced Persistent Threats in progress